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大量的研究证实急性冠状动脉综合征(ACS)患者合并肾功能异常较为常见,肾功能不全是ACS患者不良预后的独立危险因素,然而其具体的机制目前还不是很清楚。肾功能状态影响着ACS患者的治疗策略,包括介入、抗栓及抗凝药物的使用等。现对肾功能不全造成不良预后的相关病理生理机制及ACS合并肾功能不全患者的治疗现状做一综述,重视ACS患者的肾功能评估,以其更好地指导治疗,改善患者预后。
Numerous studies have demonstrated that renal dysfunction is common in patients with acute coronary syndrome (ACS). Renal insufficiency is an independent risk factor for poor prognosis in patients with ACS. However, its exact mechanism is not yet clear. Renal function affects the treatment strategy in patients with ACS, including intervention, antithrombotic and anticoagulant use. Now on the renal dysfunction caused by the adverse prognosis of the relevant pathophysiological mechanisms and ACS with renal insufficiency in patients with treatment status are reviewed, emphasis on ACS patients with renal function assessment, to better guide the treatment and improve the prognosis of patients.