PML小体,亦称为核小体(NBs),是位于细胞核内的一些特异性区域,其内含有一些在人类多种疾病(从自身免疫性疾病、白血病、肿瘤到病毒感染性疾病)的发生中发挥重要作用的蛋白质。近来的研究证据表明这些小体还与细胞的基本生物学功能如染色质结构、转录调控、凋亡及DNA修复有关。最近我们在这个领 PML bodies, also known as nucleosomes (NBs), are specific regions located in the nucleus that contain a number of genes that are involved in various human diseases (from autoimmune diseases, leukemias, tumors to viral infectious diseases) Occurred in the play an important role in the protein. Recent evidence suggests that these bodies are also involved in the basic biological functions of cells such as chromatin structure, transcriptional regulation, apoptosis and DNA repair. Recently we are in this collar