目的探讨肝门部胆管癌单双侧引流介入治疗的临床疗效。方法收集2013年1月至2014年2月我院收治的肝门部胆管癌58例患者资料,将患者随机分为单侧引流组和双侧引流组,均进行6、12个月的随访,比较治疗效果。结果双侧引流组患者的治疗效果明显优于单侧引流组;但同时间段单侧引流组患者的生存率高于双侧引流组,差异均有统计学意义(均P<0.05)。结论单双侧引流的方法,可减少患者病程中入院次数,提高患者生活质量,降低术后病死率。 Objective To investigate the clinical effect of interventional therapy of hilar cholangiocarcinoma by single and double drainage. Methods Fifty-eight patients with hilar cholangiocarcinoma admitted to our hospital from January 2013 to February 2014 were enrolled. Patients were randomly divided into unilateral drainage group and bilateral drainage group. All patients were followed up for 6 and 12 months, Compare treatment effects. Results The treatment effect in patients with bilateral drainage was significantly better than that in patients with unilateral drainage. However, the survival rate in patients with unilateral drainage in the same period was significantly higher than that in patients with bilateral drainage (all P <0.05). Conclusion Single and double drainage methods can reduce the number of patients during the course of admission, improve patient quality of life and reduce postoperative mortality.