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痤疮宝口服液急性毒性试验，昆明种小鼠口服给药最大耐受量为178．4g／kg，未见明显毒副作用。长期毒性试验，大鼠按33．9g／kg·d，1784g／kg．d的剂量连续给药4周，各组无动物死亡，动物外观、体重增长、血象、肝肾功能又脏器指数与对照组比较无异常。病理报告高、低剂量组与对照组比较，对胃肠粘膜有一定毒性作用，停药2周后再查，病检正常，提示此种毒性作用是可逆的。
The acute toxicity test of acne treasure oral liquid, Kunming mice oral administration of the maximum tolerated dose of 178.4g/kg, no obvious toxic side effects. For the long-term toxicity test, rats were treated with 33.9 g/kg·d, 1784 g/kg. The dose of d was continuously administered for 4 weeks. No animal died in each group. There was no abnormality in the appearance, weight gain, blood picture, liver and kidney function, and organ index of the animals compared with the control group. The pathology report showed that the high- and low-dose groups had certain toxic effects on the gastrointestinal mucosa compared with the control group. After 2 weeks of drug withdrawal, the disease examination was normal, suggesting that the toxicity was reversible.