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目的调查北京首钢公司在职及部分退休职工脊柱关节病(SpA)、强直性脊柱炎(AS)患者的HLA-B27阳性率。方法制定SpA问卷调查表,对首钢公司15357例职工以非抽样普查方式进行调查。筛出疑似者进行HLA-B27及骶髂关节X线检查。SpA的分类标准采用2009年ASAS标准。结果确诊脊柱关节病68例,其中HLA-B27阳性64例,阳性率为94.12%。确诊强直性脊柱炎38例,HLA-B27阳性34例,阳性率为89.47%。结论对于疑似患者进行HLA-B27检测,有助于脊柱关节病的早期诊断及与其他疾病相鉴别。
Objective To investigate the prevalence of HLA-B27 in patients with spondyloarthropathy (SpA) and ankylosing spondylitis (AS) in Beijing Shougang Company. Methods A SpA questionnaire was established to investigate 15357 workers in Shougang Company by means of non-sampling survey. Suspected persons were screened for HLA-B27 and sacroiliac joint X-ray examination. SpA classification criteria using the 2009 ASAS standard. The results confirmed 68 cases of spondyloarthropathy, including HLA-B27-positive in 64 cases, the positive rate was 94.12%. 38 cases of ankylosing spondylitis were diagnosed, 34 cases of HLA-B27 positive, the positive rate was 89.47%. Conclusion The detection of HLA-B27 in suspected patients is helpful for the early diagnosis of spondyloarthropathies and the identification of other diseases.