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目的 :探讨巯甲丙脯酸对急性肾小球肾炎的治疗作用。方法 :将我院 1993年元月～ 1998年 10月住院急性肾小球肾炎患儿 90例 ,随机分成两组 ,其中治疗组 5 0例 ,对照组 40例。治疗组在应用休息、饮食、抗生素 ,对症处理的基础上加用巯甲丙脯酸 ,巯甲丙脯酸的服法为每次 0 5～ 1mg/kg ,最大量不超过 12 5mg ,每日 3次 ;对照组仅采用休息、饮食、抗生素、对症处理。结果 :治疗组总有效率为 92 %明显高于对照组的 6 0 % ;治疗组平均住院天数为 17± 4 15天较对照组的 2 0±3 2 6天为短 ,且两组经统计学处理有非常显著差异。结论 :说明巯甲丙脯酸对急性肾小球肾炎有明显治疗作用
Objective: To investigate the therapeutic effect of captopril on acute glomerulonephritis. Methods: Ninety children with acute glomerulonephritis hospitalized from January 1993 to October 1998 in our hospital were randomly divided into two groups, including 50 in the treatment group and 40 in the control group. Treatment group in the application of rest, diet, antibiotics, symptomatic treatment based on the use of captopril, captopril daily service method for each 0 5 ~ 1mg / kg, the maximum does not exceed 125mg, daily 3 times; control group only rest, diet, antibiotics, symptomatic treatment. Results: The total effective rate in the treatment group was 92%, which was significantly higher than that in the control group (60%). The mean length of stay in the treatment group was 17 ± 4 days (20 ± 36 days), which was shorter than that of the control group There are very significant differences in learning process. Conclusion: This study shows that captopril has a significant therapeutic effect on acute glomerulonephritis