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目的探讨肝硬化病人的预后因素,为肝硬化病人的治疗及预后判断提供依据。方法选取梅州市人民医院及梅县人民医院2007年1月～2008年12月期间肝硬化的住院病例300例,采用回顾性队列研究方法,以确诊肝硬化的日期为随访起点,以死亡或出院的日期为随访终点。结果乙型及丙型肝炎后肝硬化肝功能损害最高;上消化道出血227例占52.6%,癌变29例占6.7%,肝性脑病57例占13.2%,肝肾综合征130例占30.2%,自发性腹膜炎194例占45.%,死亡43例占30.2%。结论肝硬化的预后取决于病因、肝实质储备功能和是否伴有严重的并发症。
Objective To investigate the prognostic factors of patients with liver cirrhosis and provide evidence for the treatment and prognosis of patients with cirrhosis. Methods A total of 300 inpatients with cirrhosis from January 2007 to December 2008 in Meizhou People’s Hospital and Meixian People’s Hospital were enrolled in this study. Retrospective cohort study was used to determine the date of liver cirrhosis as the starting point of follow-up, with death or discharge Date is the end of follow-up. Results Hepatic cirrhosis of type B and C had the most severe hepatic dysfunction. 227 cases of upper gastrointestinal bleeding accounted for 52.6%, 29 cases of carcinogenesis accounted for 6.7%, 57 cases of hepatic encephalopathy accounted for 13.2% and 130 cases of hepatorenal syndrome accounted for 30.2% , 194 cases of spontaneous peritonitis accounted for 45.%, 43 cases died of 30.2%. Conclusion The prognosis of cirrhosis depends on etiology, liver parenchymal reserve function and whether there are serious complications.