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目的：测定膀胱肿瘤患者尿中D－二聚体含量，探讨D－二聚体与膀胱肿瘤的关系及其应用价值。材料与方法：定量酶联免疫吸附试验测定43例患者。结果：肿瘤患者尿中D－二聚体平均含量高于非肿瘤患者和正常对照（P＜0.05）。非肿瘤患者与正常对照之间无显著性差异（P＞0．05）。术后肿瘤患者及非肿瘤患者尿中D－二聚体合量较术前增高（P＜0．05），肿瘤患者高于非肿瘤患者（P＜0．05）结论：膀胱肿瘤患者尿中D－二聚体含量发生改变，尿中D－二聚体可作为监测肿瘤患者的指标之一。手术创伤可导致尿中D－二聚体含量增加。
Objective: To determine the urinary D-dimer in patients with bladder cancer and explore the relationship between D-dimer and bladder cancer and its clinical value. Materials and Methods: Quantitative enzyme-linked immunosorbent assay for 43 patients. Results: The average urinary D-dimer in cancer patients was higher than that in non-tumor patients and normal controls (P <0.05). There was no significant difference between non-tumor patients and normal controls (P> 0.05). Postoperative tumor patients and non-tumor patients with increased urinary D-dimer volume compared with preoperative (P <0.05), tumor patients were higher than non-tumor patients (P <0.05) Conclusion: Urinary bladder cancer patients D-dimer content changes, urine D-dimer can be used as indicators of cancer patients. Surgical trauma can lead to increased urinary D-dimer levels.