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目的分析非酒精性脂肪肝合并2型糖尿病患者的临床状况,并探讨与其相关的因素。方法回顾性分析我院2013年3月到2014年3月治疗的100例非酒精性脂肪肝合并2型糖尿病患者的临床资料,并根据腹部B超的结果将其分为无NAFLD组和NAFLD组,然后对两组患者的年龄、病史以及病程等资料进行统计,同时还要对患者的身高、体重以及体质指数、糖化血红蛋白、肝功能、血脂、肾功能等进行相应检测分析。结果通过分析可以得出无NAFLD组的年龄要大于NAFLD组,而NAFLD组患者的糖尿病病程较短、尿酸清除率有所降低,血尿酸、丙氨酸转氨酶、天冬氨酸转氨酶、γ-谷氨酰转移酶以及体质指数等均升高,其数据均存在差异性,具有统计学意义(P<0.05)。经过分析显示,NAFLD的并发会随着年龄、病程、体质指数、肝酶的增加而增加。结论非酒精性脂肪肝病合并2型糖尿病患者存在明显的超重以及胰岛素抵抗、脂代谢紊乱等现象,因此在临床治疗上应该要重视患者减肥,要改善胰岛素抵抗、降脂、抗凝等,从而提升患者的治疗效果。
Objective To analyze the clinical status of patients with non-alcoholic fatty liver disease complicated with type 2 diabetes mellitus and to explore the related factors. Methods The clinical data of 100 patients with non-alcoholic fatty liver disease and type 2 diabetes treated in our hospital from March 2013 to March 2014 were retrospectively analyzed. According to the results of abdominal ultrasonography, they were divided into NAFLD-free group and NAFLD-treated group Then, the age, history and duration of the two groups of patients were statistically analyzed. At the same time, the patients’ height, weight and body mass index, glycosylated hemoglobin, liver function, blood lipids and renal function were also analyzed. Results The results showed that the NAFLD group was older than the NAFLD group, while the NAFLD group had a shorter duration of diabetes and lower uric acid clearance rate. Serum uric acid, alanine aminotransferase, aspartate aminotransferase, Aminoacyltransferase and body mass index were increased, the data are different, with statistical significance (P <0.05). After analysis, NAFLD concomitant increases with age, duration, body mass index, liver enzymes. Conclusion Patients with non-alcoholic fatty liver disease complicated with type 2 diabetes have obvious overweight, insulin resistance and lipid metabolism disorders. Therefore, they should pay attention to patients’ weight loss and improve insulin resistance, lipid-lowering and anticoagulant in clinical treatment so as to enhance Patient’s therapeutic effect.