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本实验证明,输精管吻合术后不育组(VIG)血清抗精子抗体阳性检出率和效价与输精管吻合育组(VFG)比较无差异(p>0.05);VIG的精子密度显著地低于VFG(p<0.01)和假手术组(SOG)p<0.001;精子膜ADA活力,VIG明显地低于SOG(p<0.01),VFG与SOG比较无差异(p>0,05);精子膜ADA活力与精子密度呈显著的负相关(r=-0.60,p<0.01);睾丸ACE活力与精子密度呈正相关(r=0.59,p<0.01),而与ADA活力呈有意义的负相关(r=-0.52,p<0.02)。因此,吻合术后不育与血清抗精子抗体效价无直接关系,而与精子密度降低、功能障碍有关。
This experiment demonstrated that the positive rate and titer of anti-sperm antibody in sterile group (VIG) were not significantly different from that in vas deferens anastomosis (VFG) (p> 0.05). The sperm density of VIG was significantly lower than VFG (P <0.01) and sham operation group (SOG) p <0.001; ADA activity of sperm membrane was significantly lower than that of SOG (P <0.01); VFG was no significant difference with SOG There was a significant negative correlation between ADA activity and sperm density (r = -0.60, p <0.01). There was a positive correlation between testicular ACE activity and sperm concentration (r = 0.59, r = -0.52, p <0.02). Therefore, anastomosis and serum anti-sperm antibody titers no direct relationship, but with reduced sperm density, dysfunction.