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目的 :分析肺癌钙化发生的相关因素及钙化在肺癌病灶内出现的意义。方法 :搜集我院1991年 11月至 1998年 11月 7年间周围型肺癌 194例 ,其中男 148例 ,女 4 6例 ,年龄 2 4~ 88岁 (中位数 60岁 )。CT发现肺癌钙化 2 4例 ,发生率为 12 .4 %。用SAS软件对各组钙化情况做相应的统计处理。结果 :( 1)各病理类型之间肺癌钙化发生率无差异 ;( 2 )大的肺癌比小的肺癌更容易发生钙化 ;( 3)年龄大的肺癌患者其病灶比年龄小患者的病灶更容易发生钙化 ;( 4 )肺或纵隔淋巴结钙化组的肺癌钙化发生率大于肺和纵隔淋巴结非钙化组的钙化发生率 ;( 5)结核好发部位 (上叶尖后段及下叶背段 )肺癌钙化发生率虽略高于非结核好发部位 ,但两者在统计学上无差异 (Mantel Heanzelχ2检验 ,χ2 =1.870 ,P =0 .171>0 .0 5)。结论 :CT诊断肺内实性占位时 ,仅凭有无钙化来确定病灶的良恶性显然易引起误诊 ,应结合病变的其他征象 ,才能最终做出正确的诊断。
Objective: To analyze the factors related to the occurrence of calcification in lung cancer and the significance of calcification in lung cancer lesions. Methods: Collected 194 cases of peripheral lung cancer between November 1991 and November of 1998 in our hospital, including 148 males and 46 females, aged 24 to 88 years (median 60 years old). CT found that 26 cases of lung calcification, the incidence was 12.4%. SAS software was used to do statistical treatment of the calcifications in each group. Results: (1) There was no difference in the incidence of lung calcification among the pathological types; (2) Larger lung cancer was more likely to be calcified than small lung cancer; (3) Older lung cancer patients had lesions that were easier than those of younger patients. Calcification occurred; (4) The calcification rate in lung or mediastinal lymph node calcification group was higher than that in non-calcified lung and mediastinal lymph nodes group; (5) Site of tuberculosis (post-tip and posterior segment of lower lobe) lung cancer Although the incidence of calcification was slightly higher than that of non-tuberculosis predilection sites, there was no statistical difference between them (Mantel Heanzel 2 test, χ 2 = 1.870, P =0.171> 0.05). Conclusion : When CT is used to diagnose lung solid lesions, it is obviously easy to diagnose the benign and malignant lesions by the presence or absence of calcification. Misdiagnosis is likely to be caused by the combination of other signs of the lesions before a correct diagnosis can be made.