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作者以前瞻性分组治疗对照的方法,观察了 ERBD-清解灵治疗与手术引流对急性重型胆管炎的临床疗效。ERBD-清解灵组20例,手术引流组18例。观察结果表明,治疗前患者均有胆道高压;胆汁与血中内毒素含量极高,纤维结合素、C_3水平远低于正常值,C 反应蛋白水平则高于正常值的4倍。经 ERBD-清解灵治疗后,以上指标均发生显著的变化并迅速恢复到正常水平。该组患者无并发症和死亡者。急症胆道手术引流组患者以上指标恢复很慢,有50%的患者发生心、肺、泌尿系统并发症,其中1例死亡。本文对 ERBD-清解灵治疗的机理进行了初步探讨。
In a prospective, group-based approach to treatment, the authors observed the clinical efficacy of ERBD-qinglingling and surgical drainage on acute severe cholangitis. 20 cases of ERBD-Qing Xie Ling group, 18 cases of surgical drainage group. The results showed that patients before treatment have biliary hypertension; bile and blood endotoxin content is extremely high, fibronectin, C 3 levels far below normal, C-reactive protein levels were higher than normal 4 times. After ERBD-Qing Jie Ling treatment, the above indicators have undergone significant changes and quickly returned to normal levels. The group of patients without complications and death. In the emergency biliary drainage group, the above indexes recovered slowly, and 50% of the patients had heart, lung and urinary complications, of which 1 died. In this paper, the mechanism of ERBD-Qing Jie Ling treatment was discussed.