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分别测定30例正常人及34例乙型慢活肝活动期及静止期的SOD、MnSOD、MDA及GST的血清含量。结果慢活肝活动期与正常人及静止期病人比较均有显著差异,说明乙型慢活肝病人的SOD、MnSOD、MDA的血清含量,与病情严重程度一致。血清GST活性与SOD有明显相关性,显示了GST在反应肝细胞损伤程度上的敏感性。
The serum levels of SOD, MnSOD, MDA and GST were measured in 30 normal subjects and 34 patients with chronic active B chronic active and quiescent, respectively. Results Compared with normal and quiescent patients, there was a significant difference in slow-active liver activity, indicating that the serum levels of SOD, MnSOD and MDA in patients with slow-acting chronic hepatitis B were consistent with the severity of the disease. Serum GST activity was significantly correlated with SOD, showing the sensitivity of GST to the degree of response to hepatocellular injury.