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对31例Ⅱa型、31例Ⅱb型、153例Ⅳ型高脂血症患者及100例年龄相近的正常人血清apoAl、B及其血脂含量进行分析,结果表明,3组高脂血症患者血清apoAl水平均明显降低,apoB及apoB/apoAl比值均明显升高;Ⅱa型高脂血症患者LDL-C明显升高,HDL-C无明显变化;Ⅱb型高脂血症患者LDL-C明显升高,HDL-C明显降低;Ⅳ型高脂血症患者HDL-C明显降低,LDL-C无明显变化;3组高脂血症患者LDL-C/HDL-C比值均明显升高。提示:高脂血症可使血清致动脉粥样硬化(As)因子升高和抗As因子降低,是As的危险因素之一。
31 cases of type Ⅱ a, 31 cases of type Ⅱ b, 153 cases of type Ⅳ hyperlipidemia and 100 age-matched normal subjects serum apoAl, B and its lipid content analysis, the results showed that three groups of patients with hyperlipidemia serum apoA and apoB / apoAl ratio were significantly increased; type IIa hyperlipidemia patients with elevated LDL-C, HDL-C no significant change; type IIb hyperlipidemia patients with elevated LDL-C HDL-C and HDL-C in patients with type IV hyperlipidemia were significantly lower than those in patients with type-IV hyperlipidemia. LDL-C / HDL-C ratio in patients with hyperlipidemia were significantly increased. It is suggested that hyperlipidemia can increase serum atherogenic factor (As) and decrease anti-As factor, which is one of the risk factors of As.