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根据最近的研究,应用噻嗪类和β阻滞剂作为首选抗高血压药物的观点正在部份改。近六年来作者应用钙拮抗剂异搏定治疗轻型和中型原发性高血压,共103例患者。在一年的长期试验中,应用不同剂量的即刻和持续释放的异搏定治疗高血压。方法和结果:1.先用异搏定240毫克的二层片,其中快速释放的90毫克为一层,缓慢释放的1.50毫克为另一层。这种新制剂每天用1~2次。在一个对照研究中研究28例患者,年龄32~62岁(平均50.5岁),为期四周,该试验也包括2个开放期,每期2周,常规应用即刻释放的异搏定,
According to recent research, the view that thiazide and beta blockers are the preferred antihypertensive agents is being partially modified. In the past six years, the author applied calcium antagonist verapamil to treat light and medium essential hypertension, a total of 103 patients. In a one-year, long-term trial, hypertension was treated with different doses of verapamil, both immediate and sustained. Methods and Results: 1. The first two-layer tablets with 240 mg of verapamil, of which 90 mg for the rapid release of a layer of slow release of 1.50 mg for another layer. This new preparation with 1 or 2 times a day. In a controlled study of 28 patients aged 32-62 years (mean, 50.5 years) for four weeks, the trial also included two open arms, two weeks of each, with immediate release of verapamil,