论文部分内容阅读
目的评价社区干预对高血压患者血压的影响,为高血压的预防控制提供参考依据。方法检索中国知网(CNKI)数据库、维普中国科技期刊数据库(VIP)、万方数据库、中国生物医学文献数据库(CBM)、Pub Med数据库和Web of Science数据库,全面收集社区干预对高血压患者血压影响的相关研究;采用Stata 12.0软件对纳入的文献进行meta分析,以干预后试验组和对照组高血压患者的收缩压和舒张压为评价指标,综合评价社区干预对高血压患者血压水平的干预效果。结果最终纳入18篇文献(中文文献11篇,英文文献7篇),累计干预人数4 716例,对照人数3 545例;meta分析结果显示,干预后社区干预组高血压患者收缩压(SMD=-0.65,95%CI=-0.89~-0.41)和舒张压(SMD=-0.51,95%CI=-0.71~-0.31)均低于对照组,差异均有统计学意义(均P<0.001);敏感性分析结果显示本研究结果具有良好的稳定性;Egger线性回归法结果显示,收缩压变化存在发表偏倚(t=-2.77,95%CI=-8.00~-1.06,P=0.014),舒张压不存在发表偏倚(t=-1.13,95%CI=-4.98~1.54,P=0.277)。结论社区干预可降低高血压患者的收缩压和舒张压,但这一结论需要大样本高质量的随机对照试验进一步予以证实。
Objective To evaluate the influence of community intervention on the blood pressure in hypertensive patients and provide a reference for the prevention and control of hypertension. Methods CNKI database, VIP database, Wanfang database, CBM database, Pub Med database and Web of Science database were collected to collect the data of community interventions on the blood pressure in hypertensive patients The Stata 12.0 software was used to carry out a meta-analysis of the included literatures. Based on the systolic and diastolic blood pressure of the experimental group and the control group, the intervening interventions were used to evaluate the effects of community intervention on the blood pressure level in hypertensive patients effect. Results: There were 18 literatures (11 in Chinese and 7 in English), with a total of 4 716 interventions and 3 545 controls. Meta analysis showed that systolic blood pressure (Hs + 0.65, 95% CI = -0.89 ~ -0.41) and diastolic blood pressure (SMD = -0.51, 95% CI = -0.71 ~ -0.31) were significantly lower than those of the control group (all P <0.001) Sensitivity analysis results showed that the results of this study have good stability; Egger linear regression analysis showed that there are publication bias changes in systolic blood pressure (t = -2.77,95% CI -8.00 ~ -1.06, P = 0.014), diastolic blood pressure There was no publication bias (t = -1.13, 95% CI = -4.98-1.54, P = 0.277). Conclusion Community intervention can reduce systolic and diastolic blood pressure in hypertensive patients, but this conclusion requires further confirmation by large, high-quality randomized controlled trials.