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近年来的研究,发现某些再障患者的病因与免疫学机制有关,我们试用长程左旋眯唑作为免疫抑制剂治疗了两例再障,获得临床及血液学缓解。例1 李××,女性,31岁,因面色苍白伴鼻衄、牙龈出血半年,于1982年9月24日入院。体检:贫血貌,四肢皮肤有散在出血点及瘀斑,全身浅在淋巴结不肿大,心肺正常,肝脾肋下未及。血常规:红细胞307万,血红蛋白8.9g,白细胞2,500～3,000,分类中性粒细胞52%,淋巴细胞45%,嗜酸粒细胞2%,单核细胞1%,血小板2.6万,网织红细胞1.2%。骨髓象:有核细胞增生低下,粒、红系列均受抑,淋巴细胞65%,全片巨核细胞未见。诊断矗再生障碍性贫血“。住院经过:作糖水
In recent years, some patients with aplastic anemia found that the etiology and immunological mechanisms, we try to use long-range levodazole as an immunosuppressive agent in the treatment of two cases of aplasia, access to clinical and hematological relief. Example 1 Lee × ×, female, 31 years old, pale, accompanied by epistaxis, gingival bleeding for six months, was admitted on September 24, 1982. Physical examination: anemia appearance, scattered limbs and bleeding spots and ecchymosis, systemic superficial lymph nodes is not enlarged, normal heart and lungs, liver and spleen ribs under. Blood: 3.07 million red blood cells, hemoglobin 8.9g, 2,500 to 3,000 leukocytes, classification of neutrophils 52%, 45% of lymphocytes, eosinophils 2%, monocytes 1%, platelets 26000, reticulocytes 1.2 %. Bone marrow: low proliferation of nucleated cells, granule, red series were suppressed, 65% of lymphocytes, the whole piece of megakaryocytes was not seen. Diagnosis of aplastic anemia ”. After hospitalization: as syrup