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我们用放射免疫法对87例各种急慢性肝病患者进行了E_2、T、LH、FSH及PRL的测定,并设30例正常人做对照组,综合各临床指标的观察,对肝病时上述各种激素的变化及其与肝病三联症之间的关系作一探讨。性激素的变化多见于慢性肝病患者,急性肝炎患者与正常人无显著性差异。雌二醇在慢性肝炎32%高于正常。肝硬化患者一般较正常人为高,但在合并腹水或近期内大量输血的病人雌二醇不高甚至低于正常,在无腹水的肝硬化病人E_2显著高于正常。E_2的增高与肝功能之间未发现良好的相关性,血浆T水平较正常人显著降低,但E_2与T的变化与三联征的发生均无良好的相关性,E_2与T的比值在三联征者较无三朕征者显著升高
We used radioimmunoassay in 87 cases of various acute and chronic liver disease patients with E_2, T, LH, FSH and PRL determination, and 30 cases of normal control group, the comprehensive observation of the clinical indicators of liver disease, the above Changes of Hormone and Its Relationship with Hepatitis C Triad. Sex hormone changes more common in patients with chronic liver disease, acute hepatitis patients and normal no significant difference. Estradiol is 32% higher than normal in chronic hepatitis. Patients with cirrhosis are generally higher than normal, but in patients with ascites or blood transfusion in the near future, estradiol is not high or even below normal, and E_2 in patients with cirrhosis without ascites is significantly higher than normal. No significant correlation was found between the increase of E_2 and liver function, and the plasma T level was significantly lower than that of normal people. However, the changes of E_2 and T were not correlated well with the occurrence of triad, and the ratio of E_2 to T was in triad There was a significant increase in those who did not show any signs of illness