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羟基脲是100多年前(1869)合成的简单有机化合物,但仅在近10年前才发现其具有抗瘤作用,且能特异性地抑制脱氧核糖核酸的合成,有一定的特点,临床应用证明对慢性粒细胞型白血病等有肯定的疗效。此药由广东省医药工业研究所合成,中山医学院药理教研组及肿瘤研究所药物治疗室、肿瘤医院实验室在省医药工业研究所同志的协作下,进行了抗癌作用及药理研究工作,现将结果报告如下。该药已于
Hydroxyurea is a simple organic compound synthesized more than 100 years ago (1869), but it was only found in the past 10 years ago that it has anti-tumor effect, and can specifically inhibit the synthesis of DNA, has certain characteristics, clinical application proves There is a positive effect on chronic myeloid leukemia. The medicine was synthesized by the Guangdong Provincial Institute of Pharmaceutical Industry. The pharmacological teaching and research group of Sun Yat-sen Medical College and the drug treatment room of the Cancer Institute and the Cancer Hospital Laboratory collaborated with the comrades of the Provincial Institute of Pharmaceutical Industry to conduct anticancer and pharmacological research. Report the results as follows. The drug has been