论文部分内容阅读
采用肌球蛋白ＡＴＰ酶（ｍＡＴＰ酶）组化将肌纤维分为Ⅰ、ⅡＡ和ⅡＢ三种类型，通过慢性常压和减压间断缺氧大鼠模型，观察慢性缺氧（分别缺氧１个月和３个月）大鼠膈肌纤维类型的适应性变化，并与肢体肌肉进行比较。结果表明，慢性缺氧大鼠膈肌纤维由酵解型向氧化型转化，主要表现为ⅡＡ纤维比例上升（Ｐ＜０．０５）和ⅡＢ（Ｐ＜０．０５－０．０１）下降，肋膈肌变化大于脚膈肌和肢体肌肉。肌肉间适应性变化的差异可能与其功能要求不同有关。
The myofibers were divided into three groups Ⅰ, ⅡA and ⅡB by histochemistry of myosin ATPase (mATPase). Chronic hypoxia (hypoxia for 1 month And 3 months) rat adaptive changes in diaphragmatic muscle fiber type, and compared with limb muscle. The results showed that the diaphragmatic muscle fibers of the chronic hypoxic rats transformed from glycolysis to oxidized type, and the main manifestations were the increased ratio of Ⅱ A fibers (P <0.05) and ⅡB (P <0.05-0.01) Change is greater than the foot diaphragm and limb muscle. Differences in adaptive changes between muscles may be related to their functional requirements.