强蛋白銀及弱蛋白銀的含量測定,中国药典及B.P.(1958),B.P.C.(1954)都是采用烧灼破坏、灰化后,以硝酸溶解,硫酸鉄铵作指示剂,再以硫氰酸銨滴定。这个方法的优点是,終点明显,易于观察,但操作繁复,时間很久,如在没有煤气設备的地点,工作上是存在一定困难的。国内外学者对蛋白銀含量测定的簡化手續,亦曾提出过改进方法,但据我們試驗,因溶液大都具有較深顏色,終点不易控制。蛋白銀含量测定的簡化,問題在于溶液顏色是否能成为無色,因此我們进行了多次試驗,最后以硫酸破坏蛋白質,再加硝酸酸化,这样終点明确,操作时间大为縮短,結果很好。茲將测定方法介紹于后: 精密称取本品約0.5g,加蒸溜水10ml,溶解后, The determination of the content of strong protein silver and weak protein silver, Chinese Pharmacopoeia and BP (1958), BPC (1954) were performed after caking, ashing, dissolution with nitric acid, ammonium sulfate as indicator, and ammonium thiocyanate Titration. The advantage of this method is that the end point is obvious and easy to observe, but the operation is complicated and the time is long. For example, there is a certain difficulty in working without gas facilities. Domestic and foreign scholars have also proposed improvements to the simplified procedures for the determination of protein silver content, but according to our experiments, most of the solutions have darker colors and the endpoint is not easy to control. The simplification of the determination of protein silver content, the question is whether the solution color can become colorless, so we conducted a number of tests, and finally destroyed the protein with sulfuric acid, plus acidification of nitric acid, so that the end point is clear, the operation time is greatly shortened, the result is very good. We will introduce the measurement method later: Accurately weigh about 0.5g of the product, add distilled water 10ml, dissolve,