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核因子-κB(NF-κB)是调节多种炎症和免疫基因表达的一种重要的转录调节因子,其过度激活与许多病理现象有关,已引起人们广泛地关注。本文综述了NF-κB的生物学特性、功能及其与川崎病的关系。
Nuclear factor-κB (NF-κB) is an important transcriptional regulator that regulates the expression of a variety of inflammatory and immune genes. Over-activation of NF-κB has been linked to many pathological phenomena and has attracted wide attention. This article reviews the biological characteristics of NF-κB, its function and its relationship with Kawasaki disease.