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应用放射免疫和比色法,对30例血管炎患儿血中内皮素和一氧化氮浓度进行测定。结果显示:血管炎患儿急性期血中内皮素和一氧化氮浓度较正常对照组明显升高,且内皮素与一氧化氮浓度呈正相关;恢复期两者与正常对照组比较,无显著差异。提示内皮素与一氧化氮之间可能存在着一个负反馈调节机理。
Application of radioimmunoassay and colorimetric method, 30 cases of vasculitis in children with endothelin and nitric oxide concentrations were measured. The results showed that the blood levels of endothelin and nitric oxide in children with vasculitis were significantly higher than those in the normal control group, and the concentrations of endothelin and nitric oxide were positively correlated. There was no significant difference between the convalescent group and the normal control group . Tip endothelin and nitric oxide may exist between a negative feedback regulation mechanism.