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HLA系统以高度等位基因多态性为特征。在70年代初就说明它在人类研究中是一个特异性的遗传标记。国外对不同人种和民族的HLA分布调查作了大量工作。研究表明HLA抗原频率、单倍型频率以及它们的连锁不平衡等在不同民族、不同地区、不同人群间具有显著性差异。我国由五十多个民族组成,各民族的发源、迁徙和融合的过程是非常复杂的。因此进行不同民族的HLA调查,比较民族之间HLA频率分布上的差异,对探讨民族之间遗
The HLA system is characterized by a high degree of allelic polymorphism. In the early 1970s it was shown to be a specific genetic marker in human studies. A great deal of work has been done on the survey of HLA distribution among different ethnic groups and ethnic groups abroad. Studies have shown that HLA antigen frequency, haplotype frequency and their linkage disequilibrium in different ethnic groups, different regions, different populations have significant differences. Our country consists of more than 50 ethnic groups. The process of the origins, migration and integration of all ethnic groups is very complicated. Therefore, different nationalities of the HLA survey to compare ethnic differences in the distribution of HLA frequency, between the ethnic