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前人研究显示阿司匹林可降低食道腺癌风险,但其对Barrett食管(Barrett’s Esophagus,现今被认为是食管癌最大的危险因素)的影响尚鲜为人知。最新研究发现阿司匹林的使用可以明显减少Barrett食管发生的风险。Omer等开展一项病例对照研究,对434例经内窥镜初步诊断为Barrett食管的患者以及经内窥镜诊断未患Barrett食管的患者做对照研究,并分析年龄、性别、身体质量指数、病史和所用药物等危险因素。应用多因素Logistic回归分析Barrett食管的临床危险因素。结果显示,男性发生
Previous studies have shown that aspirin can reduce the risk of esophageal adenocarcinoma, but its impact on the Barrett’s Esophagus (now considered to be the largest risk factor for esophageal cancer) is still unknown. Recent studies have found that the use of aspirin can significantly reduce the risk of Barrett’s esophagus. Omer et al. conducted a case-control study and conducted a controlled study of 434 patients who were initially diagnosed with Barrett’s esophagus by endoscopy and patients who had been diagnosed without endoscopic Barrett’s esophagus and analyzed age, gender, body mass index, and medical history. And other medications and other risk factors. Multivariate logistic regression analysis was used to analyze the clinical risk factors of Barrett’s esophagus. The results show that men have developed