为了解大叶紫薇中总三萜对3T3-L1细胞葡萄糖和脂肪代谢的影响,研究了大叶紫薇中总三萜可能的降血糖作用机制。采用葡萄糖氧化酶法检测3T3-L1葡萄糖的消耗作用,使用油红O染色并通过比色定量分析3T3-L1细胞的脂肪含量。结果表明:大叶紫薇中总三萜具有促进脂肪细胞葡萄糖消耗、抑制脂肪形成及降血糖的作用。 In order to understand the effect of total triterpenoids in Lagerstroemia specious on glucose and fat metabolism in 3T3-L1 cells, the possible hypoglycemic mechanism of total triterpenoids in Lagerstroemia specious was studied. The depletion of 3T3-L1 glucose was measured by glucose oxidase method and the fat content of 3T3-L1 cells was quantified by oil red O staining and by colorimetric analysis. The results showed that the total triterpene in Lagerstroemia speciously has the effect of promoting the glucose consumption, inhibiting the formation of adipose tissue and lowering blood sugar in adipocytes.