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目的:比较口服维铁缓释片与静脉滴注蔗糖铁在治疗维持性血透患者肾性贫血中的治疗效果。方法:选取我院收治的因维持性血透引起的肾性贫血患者120例作为研究对象,随机分为口服组和静脉组,每组60人。口服组采用口服维铁缓释片进行治疗,静脉组采用静脉注射蔗糖铁进行治疗,检测治疗10周后两组患者血清蛋白、红细胞压积、血红蛋白、红细胞计数的变化情况,比较两组患者各项指标升幅之间的差异。结果:两种患者经治疗后血清蛋白、红细胞压积、血红蛋白、红细胞计数各指标均有不同幅度的上升,口服组患者治疗前后各项指标之间相比较,差异无统计学意义(P>0.05);静脉组患者治疗前后各项指标之间相比较差异,差异具有统计学意义(P<0.05)。两种患者经治疗后各项指标升幅之间相比较,差异具有统计学意义。结论:静脉注射蔗糖铁能及时补充肾性贫血患者合成血红蛋白所需的铁,改善贫血情况,对治疗由于维持性血透患者造成的肾性贫血具有较好的治疗效果,值得临床推广与应用。
OBJECTIVE: To compare the efficacy of Oral Dimethanol Sustained-Release Tablets with intravenous infusion of sucrose in the treatment of renal anemia in maintenance hemodialysis patients. Methods: 120 cases of renal anemia caused by maintenance hemodialysis in our hospital were selected as research object and randomly divided into oral group and intravenous group, 60 in each group. The oral group was treated with oral Weitie sustained-release tablets. The intravenous group was treated with intravenous sucrose iron. The changes of serum protein, hematocrit, hemoglobin and erythrocyte count were compared between the two groups after 10 weeks of treatment. The difference between the index increase. Results: After treatment, the serum protein, hematocrit, hemoglobin and erythrocyte count increased in both groups. There was no significant difference in the indexes between the two groups before and after treatment (P> 0.05 ). There was significant difference between the two groups before and after treatment (P <0.05). After treatment, the two indicators of the increase in the comparison, the difference was statistically significant. Conclusion: Intravenous injection of sucrose iron can promptly replenish the iron needed for the synthesis of hemoglobin in patients with renal anemia to improve the anemia, which has a good therapeutic effect on the treatment of renal anemia caused by maintenance hemodialysis patients, and is worthy of clinical promotion and application.