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目的:探讨小剂量米非司酮在子宫腺肌病治疗中的临床疗效。方法:回顾性分析我院收治的87例确诊为子宫腺肌病的患者资料,给予患者米非司酮10mg/d,连用6个月,疗程结束后对所有患者停药后随访6个月,观察用药前后患者疼痛程度、月经周期、经期、子宫体积等指标变化情况。结果:疗程结束后,所有患者痛经程度用药后较用药前明显减低,月经异常明显改善;减少了病情对患者活动程度的影响,明显改善并提高了患者的活动能力;缩小了患者的子宫体积,治疗前后患者的疼痛程度、痛经分级、月经周期、经期及经量、子宫体积上的比较差异显著(P<0.05或P<0.01),有统计学意义。结论:小剂量米非司酮治疗子宫腺肌病疗效显著,副作用小。
Objective: To investigate the clinical efficacy of low dose mifepristone in the treatment of adenomyosis. Methods: A retrospective analysis of 87 patients admitted to our hospital diagnosed with adenomyosis patients, given mifepristone 10mg / d, once every 6 months after the end of treatment for all patients were followed up for 6 months after stopping, Observed before and after treatment of patients with pain, menstrual cycle, menstruation, uterine volume and other indicators changes. Results: After the treatment, the degree of dysmenorrhea in all the patients was significantly lower than that before treatment, and the abnormal menstruation was obviously improved. The effect of the disease on the degree of activity of the patients was significantly reduced and the activity of the patients was significantly improved. The uterine volume, Before and after treatment, the pain degree, dysmenorrhea grade, menstrual cycle, menstrual period, menstrual flow and uterine volume were significantly different (P <0.05 or P <0.01), with statistical significance. Conclusion: The low dose mifepristone treatment of adenomyosis significant effect, side effects.