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本文测量了在7种不同稀土离子(La~(3+)、Pr~(3+)、Nd~(3+)、Dy~(3+)、Ho~(3+)、Er~(3+)和Tm~(3+))的水溶液中蛋氨酸~(13)C稀土诱导位移。利用稀土诱导位移对蛋氨酸稀土配合物构象的模拟结果表明,蛋氨酸通过离子化的羧基与稀土离子配位,Ln~(3+)—O长度为2.7A在配合物中,蛋氨酸以伸展状态存在,C_0-C_α-C_β-C_γ和C_α-C_β-C_γ-S成反式构象,C_β-C_γ-S-C_δ成旁式构象。根据稀土诱导位移方法建立的构象模型符合~1H邻位质子偶合常数和~(13)C顺磁弛豫速率的结果。
In this paper, the effects of different rare earth ions (La 3+, Pr 3+, Nd 3+, Dy 3+, Ho 3+, Er 3+, ) And Tm ~ (3+) aqueous solution of methionine ~ (13) C rare earth induced displacement. The simulation of rare earth complex methionine methionine induced displacement using methionine shows that methionine is coordinated with the rare earth ion through ionized carboxyl group, the length of Ln ~ (3 +) - O is 2.7A. In the complex, methionine exists in an extended state, C_0-C_α-C_β-C_γ and C_α-C_β-C_γ-S into the trans conformation, C_β-C_γ-S-C_δ into the conformation. The conformational model established by the method of rare earth-induced displacement accords with the results of para-1H proton coupling constant and ~ (13) C paramagnetic relaxation rate.