两文分别报告经常间歇服用利福平而引起的肝肾功能衰竭和第三次间歇服用利福平时发生的急性肾功能衰竭各一例,这两例皆获得成功的救治。利福平可有发热、寒颤、关节痛、黄疸及急性肾功能衰竭等副作用。这些副作用在连续服用利福平的疗程中不很多见,而间歇用药却屡有报导。两文中援引了文献中报导过的两例经肾活检 Both reported separate liver and kidney failure due to frequent intermittent use of rifampicin and one case of acute renal failure during the third intermittent dose of rifampicin, both of which were successfully treated. Rifampicin can have fever, chills, joint pain, jaundice and acute renal failure and other side effects. These side effects in the continuous course of taking rifampicin less common, but intermittent medication is often reported. Two articles cite two articles reported in the literature by renal biopsy