利用偏振光研究分子结构并不是新课题,早在150年前法国物理学家比奥特(J.B.Biot)就发现了石英晶体的旋光色散现象,一些有机化学家利用钠光测量旋光度早已成为一种常规的方法。然而这种技术真正有意义的应用,还是从五十年代中期开始的,当时美国的C.Djerassi教授和他的同事在这方面做了大量的工作。起先是研究含有手性环己酮的天然产物及 The use of polarized light to study molecular structure is not a new topic. As early as 150 years ago, the French physicist JB Biot discovered the phenomenon of optical discoloring of quartz crystals. Some organic chemists have already measured the optical rotation using sodium light as one A common method. However, the real and meaningful application of this technology began in the mid-1950s when Professor C.Djerassi and his colleagues in the United States did a great deal of work in this area. The first study was the natural product containing chiral cyclohexanone and