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目的:探讨妊娠期子痫前期孕妇进行胎儿监护和脐动脉血流监测与围生儿预后的关系。方法:对子痫前期孕妇进行无负荷试验(NST),其中89例进行缩宫素激惹试验(OCT),所有孕妇均行超声脐动脉血流分析、尿蛋白及肝功能检测。结果:子痫前期患者的胎儿窘迫、新生儿窒息、早产、胎儿电子监测异常及脐动脉血流异常发生率高于对照组。OCT和超声脐动脉血流分析结果显示异常者的围生儿预后不良发生率分别为64.70%和58.06%,明显高于正常者的16.36%和10.15%(P<0.05)。NST正常者和异常者的围生儿预后不良发生率无明显差异。OCT和超声脐动脉血流分析结果异常者剖宫产率明显高于正常者,差异有统计学意义(P<0.05)。结论:OCT和脐动脉血流分析对了解子痫前期孕妇胎盘功能和预测围生儿预后具有较高的临床价值。
Objective: To investigate the relationship between fetal monitoring and umbilical artery blood flow monitoring in pregnant women with preeclampsia and perinatal outcome. Methods: Pregnant women with preeclampsia underwent no-load test (NST), of which 89 patients underwent oxytocin stimulation test (OCT). All pregnant women underwent ultrasound umbilical artery blood flow analysis, urine protein and liver function tests. Results: The incidences of fetal distress, neonatal asphyxia, premature birth, abnormal fetal electronic monitoring and umbilical artery abnormalities in preeclampsia patients were higher than those in the control group. OCT and umbilical artery blood flow analysis showed that the abnormal incidence of perinatal unhealthy children were 64.70% and 58.06%, respectively, which were significantly higher than those of normal controls (16.36% and 10.15%, P <0.05). There was no significant difference in the incidence of adverse outcomes in perinatal children with normal and abnormal NST. The incidence of cesarean section was significantly higher in patients with abnormal results of OCT and ultrasound umbilical artery blood flow analysis, the difference was statistically significant (P <0.05). Conclusion: OCT and umbilical artery blood flow analysis have high clinical value in understanding the placental function of pregnant women with preeclampsia and predicting the prognosis of perinatal infants.