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目的通过分析诊断及治疗140例小儿难治性肺炎支原体肺炎(PRPP)的特点,探讨PRPP确切的诊断和有效的临床治疗方法。方法选取我院收治的PRPP小儿患者70例,以盲选法分为观察组和对照组,每组各35例。在诊断阶段,对患儿进行影响学检查以及实验室检查。治疗阶段对所有患儿进行以止咳、降温、祛痰的基本治疗。对照组在此基础上给予阿奇霉素注射液治疗;观察组加用用匹多莫德口服液联合治疗。疗程结束后对患儿的各项体征以及血清学指标进行监测、记录与分析。结果与对照组对比,观察组患儿止咳、降温以及治疗时间均较少,差异显著,有统计学意义,P<0.05;与对照组相比,观察组治疗后外周血T淋巴细胞亚群中CD8+显著减少,而CD3+和CD4+显著升高,差异有统计学意义,P<0.05。结论阿奇霉素注射液联合服用匹多莫德口服液对于小儿难治性肺炎支原体肺炎疗效显著,值得临床推广。
Objective To analyze the characteristics of PRPP in diagnosis and treatment of infantile refractory pneumonia mycoplasma pneumonia (PRPP) and to explore the exact diagnosis and effective clinical treatment of PRPP. Methods Seventy patients with PRPP in our hospital were selected and divided into observation group and control group by blind selection method, with 35 cases in each group. In the diagnostic phase, the impact of children and laboratory tests. Treatment of all children with cough, cooling, expectorant treatment of the basic. The control group was given azithromycin injection on this basis; the observation group plus pidotimod oral solution combination therapy. After treatment, the signs and serological indicators of children were monitored, recorded and analyzed. Results Compared with the control group, the observation group had less cough, cooling and treatment time, the difference was statistically significant, P <0.05; compared with the control group, the observation group after treatment of peripheral blood T lymphocyte subsets CD8 +, but CD3 + and CD4 + were significantly increased, the difference was statistically significant, P <0.05. Conclusion Azithromycin injection combined with Pidotimod oral solution for children with intractable pneumonia mycoplasma pneumonia significant effect, worthy of clinical promotion.