二型糖尿病是一种危害人类健康的疾病。维生素D与二型糖尿病之间的关系为糖尿病研究的热点,越来越多的研究表明维生素D可以有效的预防二型糖尿病。本文从观察性研究、干预性研究及遗传学研究三个方面综述了维生素D与二型糖尿病之间的关系,并从维生素D对胰腺β细胞的作用、对胰岛素抵抗的作用及其对炎症反应的影响三个方面阐述了其可能的机制。 Type 2 diabetes is a disease that endangers human health. The relationship between vitamin D and type 2 diabetes is a hot topic in diabetes research. More and more studies show that vitamin D can effectively prevent type 2 diabetes. This review summarizes the relationship between vitamin D and type 2 diabetes mellitus from three aspects of observational studies, interventional studies and genetics studies. The effects of vitamin D on pancreatic β-cells, insulin resistance and its effects on inflammation The impact of the three aspects of its possible mechanism.