许多职业性危害因素可引起皮肤色素的异常,包括物理性和化学性的,例如煤焦油类可引起色素沉着,酚类衍生物可引起色素减退等。近20年职业性皮肤色素异常的发病率有增加的趋势,它与工业中日益增多的新化合物有关。职业性皮肤色素异常的皮损往往多在暴露部位,如面部、颈三角区和双手。由于肤色迥异,皮损明显,往往造成患者心理上的较大负担,尤其对青年工人更是如此,甚至可间接地影响生产。另外皮肤色素异常往往与光敏或皮肤恶性病变有一定的关联。所以职业性皮肤 Many occupational hazards can cause skin pigment abnormalities, including physical and chemical, such as coal tar can cause pigmentation, phenolic derivatives can cause hypopigmentation and so on. The incidence of occupational cutaneous anomalies has increased in recent 20 years, and it is related to the increasing number of new compounds in the industry. Occupational skin pigmentation lesions are often more exposed parts, such as the face, neck and triangle area and hands. Due to the different skin colors, obvious skin lesions often result in a greater psychological burden on patients, especially for young workers, which can even indirectly affect production. In addition, abnormal skin pigmentation and skin often have a certain relationship between malignant lesions. So professional skin