用蔗糖作片剂包衣原料已有多年,但尚存在着一些问题,如生产周期长、工房粉尘大、消耗大量蔗糖,储藏期间易吸潮、发霉、脆裂等。近年内,国内外曾采用玉米朊、塑料、邻苯二甲酸、醋酸纤维素(CAP)等作为薄膜衣原料,但这类原料必先溶于有机溶剂,因而带来了易燃、易爆、有毒等问题。合成高聚物乳胶液(下简称乳胶液)具有较好的成膜性能,不用有机溶剂,生产过程较为安全。我们在武汉医药工业研究所薄膜 Sucrose tablets for coating raw materials for many years, but there are still some problems, such as long production cycle, workshop dust, consume a lot of sucrose, storage period is easy to absorb moisture, moldy, brittle and so on. In recent years, corn gluten, plastic, phthalic acid and cellulose acetate (CAP) have been used as film coating raw materials at home and abroad. However, such raw materials must be dissolved in organic solvents at first, resulting in flammable, explosive, Toxic and other issues. Synthetic polymer latex (hereinafter referred to as latex) has good film-forming properties, without organic solvents, the production process is more secure. We are in Wuhan Institute of Pharmaceutical Industry film