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目的:研究46例骨髓增生异常综合征(MDS)病程中ABO血型检定及抗体的变化。方法:采用血型血清学试验检测ABO血型抗原强度变化。结果:血型抗原减弱或丢失者占17例(37.0%),A抗原最容易减弱或丢失,ABO抗体也可以减弱。结论:吸收放散试验、血型物质检测及家系调查可以防止误定ABO血型。
Objective: To study the changes of ABO blood group and antibody during the course of 46 cases of myelodysplastic syndrome (MDS). Methods: Blood type serological test was used to detect the changes of ABO blood group antigen intensity. Results: 17 cases (37.0%) were found to have weakened or lost blood group antigens, A was the easiest to be weakened or lost, and ABO antibody could be weakened. Conclusion: Absorption and dissipation test, blood group test and pedigree investigation can prevent the misidentification of ABO blood group.