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患者,女,17岁,因周期性嗜睡1年,于1989年5月初诊。患者于1988年4月以来,每于行经前1～2天发生嗜睡,昼夜睡眠,反复呼唤方醒,醒后再睡。唤醒后表情茫然,言语、行走迟缓,无主动性言语。能自行起床大小便。有时连睡1～2天不吃不喝,在唤醒催促下方进少量饮食,食后又睡。嗜睡期长达6～8天。无发热及呕吐。发作终止后对病中经过基本不能回忆。每次发作过程相同。间歇期如常人。病前体健。自幼无高热惊厥、脑炎、脑外伤及抽搐等病史。15岁来月经,量中等,较有规律。查体未见异常。颅脑CT、EEG均正常。给口服利他林10mg每日3次,服药期间,嗜睡仍随月经周期发生,但持续时间缩短为3～4天,2月后自行停药,嗜睡发作同前。截至1994年3月,仍周期性发作,但嗜睡期逐渐缩短为2～3天,易唤醒,过后能部分回忆病中过程,发育正常,查体并复查EEG均正常。
Patient, female, 17 years old, due to periodic drowsiness 1 year, first visit in May 1989. Patients since April 1988, every 1 to 2 days before passing somnolence occurs, sleep day and night, repeatedly wake up, wake up and then sleep. Wake up blank expression, speech, slow walking, no proactive speech. Can get up and urinate on their own. Sometimes sleep 1 to 2 days without eating or drinking, urge to urge the bottom into a small amount of diet, after eating and sleep. Sleepiness up to 6 to 8 days. No fever and vomiting. After the onset of the disease after the basic can not remember. The same process for each attack. Intermittent as usual. Pre-sick body health. Since childhood, no fever convulsions, encephalitis, brain trauma and convulsions and other medical history. 15-year-old menstruation, the amount of medium, more regular. Physical examination showed no abnormalities. Brain CT, EEG are normal. Oral Ritalin given 10mg 3 times a day, medication, lethargy still occurs with the menstrual cycle, but the duration was shortened to 3 to 4 days after stopping their own in February, lethargic episodes with the previous. As of March 1994, still periodic attacks, but the narcolepsy period gradually reduced to 2 to 3 days, easy to wake up, after the disease can be part of the memory process, normal development, physical examination and review of EEG were normal.