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Tamm-Horsfall Glycoprotein(THG或TH糖蛋白)是一种肾脏特异的蛋白,它由亨氏袢升支及远端曲管上皮细胞内高尔基体产生。正常时有少量THG排泄于尿中,正常成人每日尿中排泄约50mg。尿THG的测定对观察肾脏(尤其是肾小管)病变的程度有帮助。为观察新生儿窒息等疾病对肾功能的影响,我们应用放射免疫法测定114例新生儿尿THG,报告如下。材料和方法健康足月新生儿54例(年龄1～7日,体重2500～4000g)。新生儿窒息40例(年龄1～10天,1分钟Apgar评分1～7分)。肺炎、颅内出血等疾病20例。均留新鲜尿,4℃保存,测定前充分混合均匀。健康新生
Tamm-Horsfall Glycoprotein (THG or TH glycoprotein) is a kidney-specific protein produced by Heinz & apos; s ascending branch and distal Golgi epithelial Golgi apparatus. A small amount of normal THG excreted in the urine, normal daily urinary excretion of about 50mg. The determination of urinary THG helps to observe the extent of the lesions in the kidneys, especially the tubules. To observe the impact of neonatal asphyxia and other diseases on renal function, we used radioimmunoassay of 114 cases of neonatal urinary tract THG, the report is as follows. Materials and Methods 54 full-term newborns (age 1-7 days, body weight 2500-4000g). Neonatal asphyxia 40 cases (age 1 to 10 days, Apgar score 1 to 7 minutes). Pneumonia, intracranial hemorrhage and other diseases in 20 cases. Keep fresh urine, 4 ℃ preservation, fully mixed before the determination. Healthy freshmen