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目的回顾分析12例肝脏血管平滑肌脂肪瘤(Hepati cangiomyolipoma,HAML)的临床特点及病理特征,为临床诊断及治疗提供参考。方法分析某中心2011年12例HAML的临床治疗经过及随访结果,结合文献复习进行讨论。结果术前缺乏特异的临床症状、体征,影像学表现多样。10例手术切除后病理确诊,2例经肝穿活检确诊后未手术,随访4个月～6年2个月,均未见复发或转移。结论 HAML临床较少见,术前明确诊断困难,治疗首选手术切除,而肝穿活检或术中快速冰冻病理检查对指导治疗有重要的意义。
Objective To retrospectively analyze the clinical features and pathological features of 12 cases of hepatic angiomyolipoma (HAML), and provide a reference for clinical diagnosis and treatment. Methods Clinical analysis of 12 cases of HAML in a center in 2011 and the follow-up results were analyzed with the review of the literature. Results Preoperative lack of specific clinical symptoms, signs, imaging performance varied. Ten cases were diagnosed pathologically after surgery, 2 cases were diagnosed by liver biopsy, and were followed up for 4 months to 6 years and 2 months without recurrence or metastasis. Conclusions HAML is rare in clinical practice. It is difficult to diagnose the disease preoperatively and is the first choice of surgical resection. The biopsy of liver biopsy or rapid frozen pathological examination during operation is of great significance to the guiding therapy.