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目的 :观察瑞格列奈降低 2型糖尿病人的空腹血糖 ,餐后 2h血糖的作用。方法 :2型糖尿病人 68例 ,随机分为治疗组 3 4例 (男 1 8,女 1 6)及对照组 3 4例 (男 1 7,女 1 7)。采用瑞格列奈 0 .5mgpotid× 4周。结果 :能有效降低 2型糖尿病人的空腹血糖 ,餐后 2h血糖的作用。有非常显著性差异 (P <0 .0 1 ) ,尚能降低糖化血红蛋白 (P <0 .0 1 )。结论 :瑞格列奈能有效降低 2型糖尿病人的空腹血糖 ,餐后 2h血糖 ,降低血脂及糖化血红蛋白 ,且无明显副作用。
Objective: To observe the effect of repaglinide on fasting blood glucose and 2h postprandial blood glucose in type 2 diabetic patients. Methods: Sixty-eight type 2 diabetic patients were randomly divided into treatment group 34 (male 18, female 16) and control group 34 (male 17, female 17). Using repaglinide 0 .5mgpotid × 4 weeks. Results: It can effectively reduce the fasting blood glucose and 2h postprandial blood glucose in type 2 diabetic patients. There is a very significant difference (P <0. 01), can still reduce the HbA1c (P <0.01). Conclusion: Repaglinide can effectively reduce fasting blood glucose, 2h postprandial blood glucose, lowering blood lipid and glycosylated hemoglobin in type 2 diabetic patients without obvious side effects.