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目的了解陕西省克山病考核达标后病情消长趋势和现状,为病因研究提供科学依据。方法采取整群随机分层抽样法,选择我省重病区富县、旬邑县;中等病区永寿县、凤县;轻病区耀州区、陇县作为调查县。每个县(区)抽取能代表该县基本病情的重发病村和历史病情相对较轻或非发病村各一个村,进行临床、心电图检查,慢型及疑似克山病患者拍摄后前位2 m距离X线胸片;并采集克山病人及健康人群粮、发、血样进行硒等微量元素含量测定;病区居民经济收入及膳食构成;调查点所在县克山病发病线索调查等项目。结果6县(区)共检出潜在型克山病131例,检出率2.30%,慢型克山病8例,检出率0.14%。粮、发、血硒含量测定结果显示克山病患者和病区健康人硒水平已接近非病区居民硒水平。结论目前,陕西省克山病病区病情呈低发稳定趋势。
Objective To understand the trend and current status of the disease after the examination of Keshan disease in Shaanxi Province and to provide a scientific basis for the study of the cause. Methods Random cluster stratified sampling method was adopted in this study. We selected Fuxian and Xunyi counties with severe illnesses in our province, Yongshou County and Fengxian Middle-Ward, and Yaozhou District and Longxian County as the surveyed counties. Each county (district) to take the county to reflect the basic condition of the re-incidence of the village and the history of the disease is relatively mild or non-incidence of the village of each village for clinical examination, ECG and chronic and suspected Keshan patients after taking the first 2 m distance X-ray; and collected Keshan patients and healthy population of food, hair, blood samples for the determination of trace elements such as selenium; Ward residents income and diet composition; investigation of the county Keshan disease incidence clues and other items. Results A total of 131 cases of latent Keshan disease were detected in 6 counties (districts), with a detection rate of 2.30% and 8 cases of chronic Keshan disease with a detection rate of 0.14%. Determination of selenium content in food, hair and blood showed that the Selenium level of Keshan disease patients and healthy people in the Ward was close to that of non-Ward residents. Conclusion At present, the condition of Keshan disease in Shaanxi province shows a trend of low incidence and stable.