日向夏是日本宫崎县生长的柑橘。此次探讨了日向夏对CYP3A活性的影响。方法:将2004年3月采摘的日向夏的果皮和果实分开,果皮以100℃水提取3h,果实以榨汁机分成果汁与残渣(内果皮)。内果皮按上述方法用水提取。以咪达唑仑及卡马西平为基质,探讨了果汁以及果皮和内果皮水提取部分 Nisaka is a citrus grown in Miyazaki, Japan. This time we investigated the effect of Nisshinchi on the activity of CYP3A. Method: The peels and fruits were harvested in March, 2004. The pericarp was extracted with water at 100 °C for 3 h. The juice was divided into juice and residue (endocarp) by a juicer. The endocarp is extracted with water as described above. Using midazolam and carbamazepine as substrates, the extraction of fruit juice and the skin and endocarp was studied.