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为探讨长期接触二硫化碳（ＣＳ２）的粘胶纺丝男工血清性激素及尿２－硫代－噻唑啶－４－羧酸（ＴＴＣＡ）水平，应用放射免疫法测定接触工人血清性激素水平及用高效液相色谱法测定工人班末尿中ＴＴＣＡ含量。以多功能气体红外监测仪定点连续监测车间ＣＳ２浓度为（１４．４０±４．６２）ｍｇ／ｍ３（６．０１～２５．３０ｍｇ／ｍ３），平均接触工龄为１０．４年。结果显示（１）接触组血清促卵泡激素〔ＦＳＨ：（１０．９４±７．３５）ＩＵ／Ｌ）〕明显高于对照组〔（７．５０±５．０７）ＩＵ／Ｌ〕；催乳素〔ＰＲＬ（５．７２±４．１８）ｎｇ／Ｌ〕则显著低于对照组〔（６．８９±４．６２）ｎｇ／Ｌ〕；血清促黄体激素（ＬＨ）、睾丸酮（Ｔ）等两组间均无统计学显著差异。但随着暴露工龄延长，ＨＬ含量明显下降。班的轮换不影响性激素水平。（２）在该接触浓度下工人班末尿ＴＴＣＡ为（１．０７２±１．０１３）ｍｇ／ｇ肌酐，随尿ＴＴＣＡ排出量增加，血清ＦＳＨ含量明显下降，存在接触－反应关系。本研究表明，现有接触水平对男工内分泌系统功能已造成一定损害。
In order to investigate the level of serum sex hormones and urinary 2-thio-thiazolidine-4-carboxylic acid (TTCA) in viscose-spun men’s long-term exposure to carbon disulfide (CS2), the level of serum sex hormones Determination of TTCA in Urine of Workers by Phase Chromatography. The multi-functional gas infrared monitor was used to continuously monitor the concentration of CS2 in the workshop (14.40 ± 4.62) mg / m3 (6.01 ~ 25.30 mg / m3) with an average exposure duration of 10.4 years. The results showed that (1) FSH (10.94 ± 7.35) IU / L in the exposed group was significantly higher than that in the control group [(7.50 ± 5.07) IU / L); prolactin 〔PRL (5.72 ± 4.18) ng / L〕 was significantly lower than that of the control group 〔(6.89 ± 4.62〕 ng / L〕; serum luteinizing hormone (LH) and testosterone There was no statistically significant difference between groups. However, with prolonged exposure to service, HL content decreased significantly. Class shifts do not affect sex hormone levels. (2) Urinary TTCA at the end of the working-class was (1.072 ± 1.013) mg / g creatinine at the contact concentration. With the increase of urinary TTCA excretion, the serum FSH content decreased obviously. There was a contact-reaction relationship. This study shows that the existing level of exposure has caused some damage to the male endocrine system function.