患者,女,40岁,腹泻三天于1994年9月12日收住院.拟以慢性结肠炎常规给予氟哌酸(FPA)治疗,首次服FPA(0.2g)约40分钟后出现全身瘙痒,以四肢为甚,同时心慌、胸闷、声音嘶哑,自觉咽部异物感,继之呕吐胃内容物.体检:T37.5℃,P90次/分,BP12/8kPa,痛苦貌,双眼浮肿青紫,以右眼明显,咽部充血水肿,全身可见广泛密集融合成片状斑疹,压之退色,心肺无异常.患者既往体健,无过敏史.考虑是FPA过敏反应,立即停用 The patient, female, 40 years old, with diarrhea admitted to hospital on September 12, 1994, was given routine treatment with norfloxacin (FPA) as chronic colitis. Systemic pruritus occurred about 40 minutes after the first dose of FPA (0.2 g) To limbs is very staggering, chest tightness, hoarseness, conscious throat foreign body sensation, followed by vomiting stomach contents. Physical examination: T37.5 ℃, P90 beats / min, BP12 / 8kPa, painful appearance, Obvious right eye, pharynx congestion and edema, the body can be seen a wide range of intensive integration into patchy rash, pressure of the fade, no abnormal heart and lung patients with past history of health, no allergy. Consider FPA anaphylaxis, immediately stop using