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目的探讨早产儿重症感染与血小板参数变化的关系。方法对72例早产儿于出生24 h内和生后7 d进行血小板参数检测,并与同期无并发症的64例早产儿的各项指标进行比较。结果出生24 h内,重症感染组血小板计数(PLT)、平均血小板体积(MPV)、平均血小板体积分布宽度(PDW)与对照组比较差异无统计学意义(P>0.01);生后7 d,重症感染组PLT明显低于对照组和24 h内(P<0.01),感染组MPV、PDW明显大于对照组和24 h内(P<0.01)。结论早产儿重症感染可能是导致血小板参数改变的一个重要原因。
Objective To investigate the relationship between severe infection and platelet parameters in premature infants. Methods 72 preterm infants were tested for platelet parameters within 24 hours of birth and 7 days after birth, and compared with 64 premature infants without complications. Results There was no significant difference in platelet count (PLT), mean platelet volume (MPV) and mean platelet volume distribution (PDW) between the severe infection group and the control group within 24 hours of birth (P> 0.01) The PLT in severe infection group was significantly lower than that in control group and within 24 h (P <0.01). MPV and PDW in infected group were significantly higher than those in control group and within 24 h (P <0.01). Conclusion Severe infection in preterm infants may be an important reason for the change of platelet parameters.