NF-κB信号通路是一个复杂的网络,该通路的异常激活可导致肿瘤相关基因的异常表达,在肿瘤的发生、发展中起着抑制细胞凋亡、促进细胞增殖、促进肿瘤转移的重要作用。目前研究表明,该信号通路与子宫内膜癌细胞凋亡、增殖、侵袭、转移、血管生成及治疗有关。本文就NF-κB信号通路与子宫内膜癌关系的研究进展做一综述。 The NF-κB signaling pathway is a complex network. Abnormal activation of this pathway leads to the abnormal expression of tumor-related genes. It plays an important role in tumorigenesis and development in inhibiting apoptosis, promoting cell proliferation and promoting tumor metastasis. The current studies show that the signal pathway and endometrial cancer cells apoptosis, proliferation, invasion, metastasis, angiogenesis and treatment. This review summarizes the progress in the study of the relationship between NF-κB signaling pathway and endometrial cancer.