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总结猪胸腺素组分5(PThF_5)治疗31例流行性出血热(EHF)的临床效果,发现该药在改善免疫功能、缓解临床症状、减轻肾脏损害等方面有一定疗效,与同期收治的对照组相比,全身症状好转时间及尿蛋白的消失时间等均明显短于对照组。对胸腺素的作用机制做了探讨,初步认为 PThF_5主要刺激功能低下的 T 细胞来调节免疫功能,促进病情的恢复。该药来源丰富,价格较便宜,使于临床推广应用。
To summarize the clinical efficacy of PThF_5 in treating 31 cases of epidemic hemorrhagic fever (EHF), we found that the drug has some curative effects in improving immune function, alleviating clinical symptoms and reducing renal damage. Compared with the control Compared with the control group, the improvement of systemic symptoms and the disappearance of urinary protein were significantly shorter than those of the control group. The mechanism of action of thymosin was discussed, initially believed that PThF_5 mainly to stimulate the dysfunction of T cells to regulate immune function and promote the recovery of the disease. The drug is rich in source, the price is cheaper, making clinical application.