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本文研究了高、低发区５１０例ＰＨＣＨＢＶ感染、家族肝癌史及与ＡＢＯ血型的关系，结果表明：１肝癌低发区与高发区一样，合并ＨＢＶ感染的ＰＨＣ患者达８０．７４％，远多于无ＨＢＶ感染者；男性多于女性；有家族肝癌史的ＰＨＣ患者占４０．００％，且合并ＨＢＶ感染的ＰＨＣ有家族肝癌史者显著多于ＨＢＶ阴性组（Ｐ＜０．０５）；２低发区ＰＨＣ中，有家族肝癌史的Ａ型血者显著多于相应对照组（Ｐ＜０．０５）。提示我国肝癌低发区ＰＨＣ发生的最重要外因亦为ＨＢＶ感染，遗传易感性则是其内因；而有ＨＢＶ感染或有家族肝癌史者是ＰＨＣ的高危人群，且后者中的Ａ型血者更为易患，对这一人群需加强监测，警惕ＰＨＣ的发生。
This study investigated the relationship between PHC HBV infection, family HCC history, and ABO blood types in 510 patients with high and low incidence areas. The results showed that: 1 In areas with low incidence of HCC and high-risk areas, PHC patients with HBV infection reached 80.74%, much more. Among those without HBV infection, males were more than females; PHC patients with a family history of hepatocellular carcinoma accounted for 40.00%, and PHC with HBV infection had significantly more family history of hepatocellular carcinoma than HBV-negative group (P<0.05); 2 In the low-incidence PHC, the type A blood with family history of hepatocellular carcinoma was significantly more than the corresponding control group (P<0.05). The most important external cause of PHC in low-incidence areas of liver cancer in China is also HBV infection, and genetic susceptibility is its internal cause; while those with HBV infection or family history of liver cancer are high-risk groups of PHC, and in the latter type of A blood type It is more vulnerable to the need for more monitoring of this group of people, alert PHC.