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目的:研究龙蔓藤茶调节血脂的作用。方法:用高脂饲料喂养雄性SD大鼠,随机分为模型组、龙蔓藤茶高剂量组37.80 g·kg-1、中剂量组12.60 g·kg-1、低剂量组6.30 g·kg-1及降脂药物组(180 mg·kg-1),连续给药30 d,观察各组大鼠体质量、血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白(HDL-C)等指标的变化。结果:各给药组体质量增长与模型组比较,差异无统计学意义(P>0.05),大鼠未出现明显中毒症状;模型组实验后的TC和TG明显高于实验前(P<0.05);给药30 d后,与模型组比较,龙蔓藤茶37.80 g·kg-1剂量组可显著降低高脂饲料大鼠血清TC和TG水平(P<0.05)。结论:龙蔓藤茶具有辅助降血脂的作用。
Objective: To study the role of dragon vine vinegar in regulating blood lipids. Methods: Male Sprague-Dawley rats were fed with high-fat diet and randomly divided into model group, Longfeng vine tea high-dose group (37.80g · kg-1), middle dose group (12.60g · kg-1) and low dose group (6.30g · kg- 1 and lipid-lowering drugs (180 mg · kg-1) for 30 days. The body weight, serum total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL- C) and other indicators of change. Results: There was no significant difference in the body weight gain between the two groups (P> 0.05), and no obvious symptoms of poisoning were found in the model groups. The levels of TC and TG in the model group were significantly higher than those before the experiment (P <0.05) (P <0.05). After 30 days of administration, compared with the model group, the content of TC and TG in serum of 37.80 g · kg-1 group was significantly decreased (P <0.05). Conclusion: Dragon vine tea has the effect of reducing blood fat.